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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TGM2 All Species: 8.79
Human Site: S538 Identified Species: 24.17
UniProt: P21980 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P21980 NP_004604.2 687 77329 S538 N L N L E P F S E K S V P L C
Chimpanzee Pan troglodytes XP_001144397 691 77767 S542 N L N L E P F S E K S V P L C
Rhesus Macaque Macaca mulatta XP_001095155 660 73996 L552 P E C G T K H L L N L N L E P
Dog Lupus familis XP_542991 687 77133 S538 N L S L E P F S E K S I P L R
Cat Felis silvestris
Mouse Mus musculus P21981 686 77043 E538 L T L D P Y S E N S I P L R I
Rat Rattus norvegicus P23606 824 90751 A647 T K K E V V L A P G A S D T V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q01841 689 77951 M538 N L S L Q P H M E Q S V P L R
Frog Xenopus laevis NP_001085410 691 77710 E540 N L T L P P Q E E K R V P L H
Zebra Danio Brachydanio rerio NP_997821 679 75754 G530 N V E L P P G G E R K V P L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.6 89.6 84.5 N.A. 84.1 32.1 N.A. N.A. 64.8 61.7 53.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 96 91.1 91.6 N.A. 91.6 47.3 N.A. N.A. 77.2 75.4 67.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 80 N.A. 0 0 N.A. N.A. 60 60 46.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 0 93.3 N.A. 0 13.3 N.A. N.A. 80 60 60 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 12 0 0 12 0 0 0 0 % A
% Cys: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 23 % C
% Asp: 0 0 0 12 0 0 0 0 0 0 0 0 12 0 0 % D
% Glu: 0 12 12 12 34 0 0 23 67 0 0 0 0 12 0 % E
% Phe: 0 0 0 0 0 0 34 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 12 0 0 12 12 0 12 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 23 0 0 0 0 0 0 0 12 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 12 12 0 0 12 % I
% Lys: 0 12 12 0 0 12 0 0 0 45 12 0 0 0 0 % K
% Leu: 12 56 12 67 0 0 12 12 12 0 12 0 23 67 0 % L
% Met: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % M
% Asn: 67 0 23 0 0 0 0 0 12 12 0 12 0 0 0 % N
% Pro: 12 0 0 0 34 67 0 0 12 0 0 12 67 0 12 % P
% Gln: 0 0 0 0 12 0 12 0 0 12 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 12 12 0 0 12 34 % R
% Ser: 0 0 23 0 0 0 12 34 0 12 45 12 0 0 0 % S
% Thr: 12 12 12 0 12 0 0 0 0 0 0 0 0 12 0 % T
% Val: 0 12 0 0 12 12 0 0 0 0 0 56 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _